Safety Information

Who qualifies — and what you need to know before starting

Read this before your intake. Your prescriber will assess all of this individually — but being informed helps you make the right decision for your health.

⚠️ Not Medical Advice: This page provides general clinical information only. It is not a substitute for professional medical advice. If you are experiencing a medical emergency, call 911 immediately. Final eligibility and safety assessment is performed by a licensed physician who reviews your individual intake.
Eligibility

Who may qualify

Based on established clinical guidelines, you may be a candidate for GLP-1 treatment if you meet one of the following:

BMI ≥ 30
Obesity — no additional conditions required
— or —
BMI ≥ 27
Plus at least one weight-related health condition:
  • Type 2 diabetes
  • Hypertension (high blood pressure)
  • Dyslipidemia (high cholesterol/triglycerides)
  • Obstructive sleep apnea
  • Cardiovascular disease

Eligibility is determined by the reviewing prescriber. Meeting BMI criteria does not guarantee a prescription.

Patient consultation with healthcare provider

Do not use if you have:

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Thyroid Cancer History

Personal or family history of medullary thyroid carcinoma (MTC). GLP-1 medications carry a boxed warning for this risk based on rodent studies.

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MEN2 Syndrome

Personal or family history of Multiple Endocrine Neoplasia syndrome type 2 (MEN2). Do not use these medications.

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Pregnancy

Not for use during pregnancy, while attempting to become pregnant, or if breastfeeding. Discontinue at least 2 months before planned pregnancy.

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Known Hypersensitivity

Known allergic reaction or hypersensitivity to semaglutide, tirzepatide, or any component of the formulation.

Common Side Effects

Most side effects are GI-related and tend to improve after the first few weeks of treatment, especially with slow titration.

  • NauseaVery common
  • VomitingCommon
  • DiarrheaCommon
  • ConstipationCommon
  • Decreased appetiteVery common
  • Injection site reactionsCommon
  • Headache / fatigueCommon

Serious Side Effects

Seek emergency care immediately for:

  • Severe, persistent abdominal pain (possible pancreatitis)
  • Swelling of face, lips, tongue, or throat; difficulty breathing (allergic reaction)
  • Lump or swelling in neck; hoarseness; trouble swallowing (possible thyroid tumor)
  • Severe upper abdominal pain, fever, jaundice (gallbladder problems)
  • Severe dehydration from persistent vomiting or diarrhea
  • Significant increase in resting heart rate

Caution With:

  • ⚠️ History of pancreatitis
  • ⚠️ Gallbladder disease or gallstones
  • ⚠️ Diabetic retinopathy
  • ⚠️ Severe GI disease
  • ⚠️ Significant kidney disease

Drug Interactions

GLP-1 medications slow gastric emptying, which can affect how quickly other oral medications are absorbed. Always disclose your full medication list to your prescriber. Key interactions to discuss:

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Insulin & diabetes medications — increased risk of hypoglycemia (low blood sugar)
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Oral contraceptives — absorption timing may be affected
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Warfarin & blood thinners — may need more frequent INR monitoring
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Medications with narrow absorption windows — discuss with prescriber

Storage & Handling

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Refrigerate

Store at 36–46°F (2–8°C). Do not freeze. Allow to reach room temperature before injection.

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Protect from Light

Keep in original packaging. Do not expose to direct sunlight or high temperatures.

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Check Expiration

Do not use after the expiration date. Discard any unused portion in an appropriate sharps container.

Start Your Intake

Your prescriber will review your specific health history before issuing any prescription.