Compounded semaglutide and compounded tirzepatide — prepared by a state-licensed compounding pharmacy, prescribed by licensed providers. Not FDA-approved. Prescription required.
GLP-1 (glucagon-like peptide-1) is a hormone naturally released by your gut after eating. These medications mimic that hormone — at therapeutic levels — to produce meaningful, sustained weight loss.
GLP-1 receptors in the brain (hypothalamus) receive signals that reduce hunger and cravings. Most patients report eating significantly less without feeling deprived.
Food moves more slowly from the stomach to the small intestine, extending the feeling of fullness after meals and reducing the drive to snack between meals.
These medications stimulate insulin release in response to meals and suppress glucagon. This helps stabilize blood sugar — especially relevant for patients with type 2 diabetes or pre-diabetes.
Compounded semaglutide is a GLP-1 receptor agonist prepared by a state-licensed compounding pharmacy. GLP-1 receptor agonists work by mimicking the GLP-1 hormone — signaling the brain to reduce appetite, slowing gastric emptying, and supporting blood sugar regulation.
Compounded semaglutide is not FDA-approved and is not the same as commercially manufactured brand-name drugs. Safety and efficacy have not been established for this compounded formulation. FDA-approved GLP-1 products have established safety and efficacy; compounded versions do not carry the same regulatory assurances.
Subcutaneous self-injection in the abdomen, thigh, or upper arm.
Starts at 0.25mg/week, increases over 16+ weeks to 2.4mg maintenance.
Multi-dose vial with syringes and supplies included every month.
Monthly clinical review, dose adjustments, and ongoing support.
| Weeks | Dose | Phase | Monthly Price |
|---|---|---|---|
| 1–4 | 0.25 mg/week | Initiation | $249/mo |
| 5–8 | 0.5 mg/week | Titration | $249/mo |
| 9–12 | 1.0 mg/week | Titration | $299/mo |
| 13–16 | 1.7 mg/week | Titration | $329/mo |
| 17+ | 2.4 mg/week | Maintenance | $349/mo |
Your prescriber may adjust this schedule based on tolerability and response. Dose increases are not automatic — they require provider approval at each monthly check-in.
Compounded semaglutide is not FDA-approved. FDA approval means a drug has been reviewed by the agency for safety and efficacy in the specific form being sold. Compounded medications do not go through that review process. Do not assume that compounded semaglutide will produce the same outcomes as FDA-approved products. Discuss all options — including FDA-approved alternatives — with your prescribing provider.
Tirzepatide is a dual GIP/GLP-1 receptor agonist. By activating both the GIP and GLP-1 receptors simultaneously, tirzepatide has produced the largest average weight loss of any approved medication to date.
Compounded tirzepatide is a dual GIP/GLP-1 receptor agonist prepared by a state-licensed compounding pharmacy. By activating both the GIP and GLP-1 receptors, it works through two complementary pathways involved in appetite regulation and blood sugar control. Compounded tirzepatide is not FDA-approved and is not the same as commercially manufactured brand-name products. Safety and efficacy have not been established for this compounded formulation.
Same administration method as semaglutide — subcutaneous self-injection.
Starts at 2.5mg/week, increases every 4 weeks to a maximum of 15mg.
Activates both GIP and GLP-1 receptors — distinct from semaglutide's single-receptor action.
Monthly clinical reviews and dose management included.
| Weeks | Dose | Phase | Monthly Price |
|---|---|---|---|
| 1–4 | 2.5 mg/week | Initiation | $349/mo |
| 5–8 | 5.0 mg/week | Titration | $399/mo |
| 9–12 | 7.5 mg/week | Titration | $449/mo |
| 13–16 | 10.0 mg/week | Titration | $499/mo |
| 17–20 | 12.5 mg/week | Titration | $499/mo |
| 21+ | 15.0 mg/week | Maintenance | $499/mo |
Dose progression requires provider approval at each monthly check-in. Your provider may slow titration if side effects are significant.
Compounded tirzepatide is not FDA-approved. FDA-approved products have been reviewed for safety and efficacy in the specific form being sold; compounded medications have not. Do not assume that compounded tirzepatide will produce the same outcomes as FDA-approved products. Discuss all options — including FDA-approved alternatives — with your prescribing provider.
Your prescriber will make this determination based on your individual health profile. Here's how the two options compare.
| Compounded Semaglutide | Compounded Tirzepatide | |
|---|---|---|
| Mechanism | GLP-1 receptor agonist | Dual GIP + GLP-1 agonist |
| Injection frequency | Once weekly | Once weekly |
| Starting dose | 0.25 mg/week | 2.5 mg/week |
| Max dose | 2.4 mg/week | 15.0 mg/week |
| FDA-approved | ✗ No (compounded) | ✗ No (compounded) |
| Starting monthly price | $249/mo | $349/mo |
| Max monthly price | $349/mo | $499/mo |
Compounded medications are not FDA-approved and are not the same as commercially manufactured brand-name drugs. Safety and efficacy have not been established for compounded formulations. Individual results will vary significantly.
Not sure which is right for you? Your prescriber will recommend the appropriate option after reviewing your intake.
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