Two compounded GLP-1 options for medically supervised weight management

Compounded semaglutide and compounded tirzepatide — prepared by a state-licensed compounding pharmacy, prescribed by licensed providers. Not FDA-approved. Prescription required.

Semaglutide Tirzepatide
Important disclosure: Compounded medications are prepared by state-licensed compounding pharmacies and are not FDA-approved products. They are not the same as commercially manufactured brand-name drugs. Safety and efficacy have not been established for these compounded formulations. A valid prescription from a licensed provider is required.

The science behind GLP-1 medications

GLP-1 (glucagon-like peptide-1) is a hormone naturally released by your gut after eating. These medications mimic that hormone — at therapeutic levels — to produce meaningful, sustained weight loss.

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Appetite Suppression

GLP-1 receptors in the brain (hypothalamus) receive signals that reduce hunger and cravings. Most patients report eating significantly less without feeling deprived.

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Slows Gastric Emptying

Food moves more slowly from the stomach to the small intestine, extending the feeling of fullness after meals and reducing the drive to snack between meals.

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Blood Sugar Regulation

These medications stimulate insulin release in response to meals and suppress glucagon. This helps stabilize blood sugar — especially relevant for patients with type 2 diabetes or pre-diabetes.

Compounded injectable medication vials and syringe

Compounded Semaglutide

Compounded semaglutide is a GLP-1 receptor agonist prepared by a state-licensed compounding pharmacy. GLP-1 receptor agonists work by mimicking the GLP-1 hormone — signaling the brain to reduce appetite, slowing gastric emptying, and supporting blood sugar regulation.

Compounded semaglutide is not FDA-approved and is not the same as commercially manufactured brand-name drugs. Safety and efficacy have not been established for this compounded formulation. FDA-approved GLP-1 products have established safety and efficacy; compounded versions do not carry the same regulatory assurances.

Starting at $249/month
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Once-Weekly Injection

Subcutaneous self-injection in the abdomen, thigh, or upper arm.

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Gradual Titration

Starts at 0.25mg/week, increases over 16+ weeks to 2.4mg maintenance.

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Ships Monthly

Multi-dose vial with syringes and supplies included every month.

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Provider Check-Ins

Monthly clinical review, dose adjustments, and ongoing support.

Get Started See Pricing

Standard Titration Schedule

WeeksDosePhaseMonthly Price
1–40.25 mg/weekInitiation$249/mo
5–80.5 mg/weekTitration$249/mo
9–121.0 mg/weekTitration$299/mo
13–161.7 mg/weekTitration$329/mo
17+2.4 mg/weekMaintenance$349/mo

Your prescriber may adjust this schedule based on tolerability and response. Dose increases are not automatic — they require provider approval at each monthly check-in.

Important: Compounded vs. FDA-Approved

Compounded semaglutide is not FDA-approved. FDA approval means a drug has been reviewed by the agency for safety and efficacy in the specific form being sold. Compounded medications do not go through that review process. Do not assume that compounded semaglutide will produce the same outcomes as FDA-approved products. Discuss all options — including FDA-approved alternatives — with your prescribing provider.

Medical treatment and clinical care

Compounded Tirzepatide

Tirzepatide is a dual GIP/GLP-1 receptor agonist. By activating both the GIP and GLP-1 receptors simultaneously, tirzepatide has produced the largest average weight loss of any approved medication to date.

Compounded tirzepatide is a dual GIP/GLP-1 receptor agonist prepared by a state-licensed compounding pharmacy. By activating both the GIP and GLP-1 receptors, it works through two complementary pathways involved in appetite regulation and blood sugar control. Compounded tirzepatide is not FDA-approved and is not the same as commercially manufactured brand-name products. Safety and efficacy have not been established for this compounded formulation.

Starting at $349/month
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Once-Weekly Injection

Same administration method as semaglutide — subcutaneous self-injection.

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Gradual Titration

Starts at 2.5mg/week, increases every 4 weeks to a maximum of 15mg.

Dual Mechanism

Activates both GIP and GLP-1 receptors — distinct from semaglutide's single-receptor action.

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Provider Check-Ins

Monthly clinical reviews and dose management included.

Get Started See Pricing

Standard Titration Schedule

WeeksDosePhaseMonthly Price
1–42.5 mg/weekInitiation$349/mo
5–85.0 mg/weekTitration$399/mo
9–127.5 mg/weekTitration$449/mo
13–1610.0 mg/weekTitration$499/mo
17–2012.5 mg/weekTitration$499/mo
21+15.0 mg/weekMaintenance$499/mo

Dose progression requires provider approval at each monthly check-in. Your provider may slow titration if side effects are significant.

Important: Compounded vs. FDA-Approved

Compounded tirzepatide is not FDA-approved. FDA-approved products have been reviewed for safety and efficacy in the specific form being sold; compounded medications have not. Do not assume that compounded tirzepatide will produce the same outcomes as FDA-approved products. Discuss all options — including FDA-approved alternatives — with your prescribing provider.

Which medication is right for you?

Your prescriber will make this determination based on your individual health profile. Here's how the two options compare.

Compounded Semaglutide Compounded Tirzepatide
MechanismGLP-1 receptor agonistDual GIP + GLP-1 agonist
Injection frequencyOnce weeklyOnce weekly
Starting dose0.25 mg/week2.5 mg/week
Max dose2.4 mg/week15.0 mg/week
FDA-approved✗ No (compounded)✗ No (compounded)
Starting monthly price$249/mo$349/mo
Max monthly price$349/mo$499/mo

Compounded medications are not FDA-approved and are not the same as commercially manufactured brand-name drugs. Safety and efficacy have not been established for compounded formulations. Individual results will vary significantly.

Not sure which is right for you? Your prescriber will recommend the appropriate option after reviewing your intake.

Start Your Intake

What you need to know before starting

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Do Not Use If

  • Personal/family history of MTC thyroid cancer
  • History of MEN2
  • Pregnant or planning pregnancy
  • Breastfeeding
  • Known hypersensitivity to the ingredient
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Common Side Effects

  • Nausea (especially early in titration)
  • Vomiting, diarrhea, constipation
  • Decreased appetite
  • Injection site reactions
  • Headache, fatigue
Read Full Safety Information →